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Home  /   Forum   /   Genfit   /   Koers Genfit 2017

Aandeel Genfit PSE:GNFT.FR, FR0004163111

Laatste koers (eur) Verschil Volume
3,940   -0,040   (-1,01%) Dagrange 3,905 - 4,005 169.890   Gem. (3M) 312,7K

Koers Genfit 2017

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259 Posts
Pagina: «« 1 2 3 4 5 6 ... 13 »» | Laatste | Omlaag ↓
  9. TraderRon 2 maart 2017 15:37
    quote:

    TP66 schreef op 2 maart 2017 15:24:

    Weel geen overname moeten we afwachten een premie van 35a40% dan kom je op rond de 30 euro
    In de biotecht moet je eerder aan de 200% overname bonus denken.
    Concullega (ook nash) is tijdje terug met 500% bonus overgenomen.

    Is overigens al de zoveelste storm in paar maanden.
    Nu voor het eerst met naam van de potentiële koper.
    maw er zal vast wel echt iets spelen.
  11. [verwijderd] 2 maart 2017 15:43
    quote:

    TraderRon schreef op 2 maart 2017 15:37:

    [...]
    In de biotecht moet je eerder aan de 200% overname bonus denken.
    Concullega (ook nash) is tijdje terug met 500% bonus overgenomen.

    Is overigens al de zoveelste storm in paar maanden.
    Nu voor het eerst met naam van de potentiële koper.
    maw er zal vast wel echt iets spelen.
    Waar rook is is vuur.
  12. [verwijderd] 2 maart 2017 16:57
    By William Canny
    (Bloomberg) -- Sanofi, Novartis and Shire could all be
    potentially interested in acquiring Genfit, Kepler Cheuvreux
    Event Driven desk says in emailed comments.

    * Adds that Genfit may have already engaged in early talks
    with some pharmaceutical companies
    * Value Genfit based on the potential of Elafibranor, and its
    simple blood test to diagnose NASH patients
    * Assume that in 2018, Genfit will find two different partners
    to market its diagnostic test and Elafibranor
    * Base-case scenario valuation of Genfit based on the risk-
    adjusted NPVs of the diagnostic test and Elafibranor is
    EU48/share
    * Company could be valued at EU65/share in a takeover
    situation
    * Genfit was added to Kepler M&A Candidate List in Jan.
    RELATED

    * Novartis Said in Talks to Acquire France’s Genfit:
    StreetInsider
    * Genfit Soars on Report Novartis in Talks to Buy Biotech Co.
  15. [verwijderd] 2 maart 2017 20:46
    Dit gaat vrijwel zeker een overname door Novartis worden: and Genfit's compound is "probably the second most advanced compound in development today" "http://m.timesofindia.com/business/international-business/genfit-stock-poised-for-best-day-in-3-yrs-on-potential-novartis-deal/articleshow/57433225.cms
  18. [verwijderd] 3 maart 2017 07:43
    In latest months, giant drugmakers together with Allergan, Gilead and Novartis have collectively spent billions of buying or licensing medicines designed to deal with a liver disease that few have heard of — non-alcoholic steatohepatitis, or Nash.

    This superior type of fatty liver disease causes scarring and irritation of the liver and is assumed to have an effect on greater than 16m within the US, in line with Bernstein, the funding financial institution.

    In probably the most critical instances, the sickness causes deadly cirrhosis, whereas additionally growing an individual’s probabilities of creating liver most cancers or coronary heart disease. The US Centers for Disease Control believes there are roughly 20,000 fatalities every year from continual liver disease or cirrhosis that aren’t associated to alcoholism.

    Drugmakers are betting that the variety of with Nash — which is extra widespread in obese — will rise dramatically within the coming years due to the worldwide weight problems epidemic. Some analysts are predicting the worldwide marketplace for Nash medicines might be value as a lot as $35bn a 12 months at its peak.

    There aren’t any accepted medication to deal with the situation however pharmaceutical teams are learning greater than 25 experimental compounds in people, with 4 medicines both being studied in section III medical trials, or about to enter this remaining stage of testing.

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    Of the massive drugmakers, Allergan is furthest forward, having spent $1.7bn to accumulate Tobira, a San Francisco biotech group, in November final 12 months. Tobira’s primary medication, Cenicriviroc, will enter section three trials later this 12 months with outcomes anticipated as early as 2019.

    Allergan lately acquired one other smaller Nash-focused drugmaker, Arkana, for $50m.

    “Nash is now the leading cause of liver cirrhosis and cancer, having taken over from hepatitis C,” says Dr David Nicholson, Allergan’s chief analysis and growth officer. “And at the moment, there’s nothing out there to treat it.”

    Gilead has entered the sphere too, lately buying Nimbus for as much as $1.2bn, whereas additionally investing closely in its inner analysis efforts. The West Coast-based biotech firm has already had large success with its remedies for hepatitis C, one other doubtlessly deadly liver disease.

    Several different well-known pharmaceutical teams, together with Novo Nordisk and Shire are working on Nash medication at an earlier stage of growth.

    However, the 2 firms which can be most superior don’t come from the ranks of massive pharma: Intercept Therapeutics, a New York-based biotech group, and GenFit, its French rival.

    I’M SCEPTICAL AS AS TO WHETHER [TAKING A DRUG FOR LIFE] IS DEFINITELY WANTED FOR MOST INDIVIDUALS

    Shares in Intercept jumped 13 per cent final week after the corporate stated it had redesigned a late-stage medical trial of its drug, obeticholic acid, in a approach that may make it simpler for the examine to succeed.

    Following discussions with the US Food and Drug Administration, Intercept stated the trial should now present that the drug can both resolve Nash or enhance “fibrosis” — the medical time period for liver scarring. Previously, the corporate would have needed to show the drugs may do each.

    Intercept additionally stated it could be capable to analyse the information as soon as it had enrolled 750 sufferers, moderately than 1,400, after the method of recruiting sufferers to the trial took longer than the corporate had initially anticipated

    The adjustments replicate the flexibleness of regulators on the FDA, who need to encourage drugmakers to put money into researching medicines for the untreatable situation earlier than the variety of victims will increase quickly.

    However, the sluggish recruitment to Intercept’s trial is indicative of one of many greatest hurdles going through Nash drugmakers: the disease could be very troublesome to diagnose.

    The overwhelming majority of individuals don’t realise they’ve the “silent” disease, which solely causes signs resembling jaundice, fatigue and weight reduction within the very late phases.

    Doctors generally suspect a affected person has Nash once they have elevated liver enzymes of their blood or once they spot abnormalities throughout ultrasound scans.

    But the one sure-fire approach of diagnosing the disease is to hold out a liver biopsy — a posh, invasive process that requires an anaesthetic. In uncommon instances, the biopsy could cause bleeding that requires a transfusion or surgical procedure.

    Many sufferers are reluctant to bear the process, which poses an issue not only for recruiting them to medical trials, but in addition convincing in the actual world to get examined for the situation.

    Podcast

    High hopes that new immunotherapy medication would show to have advantages over poisonous chemotherapy had been dashed by large-scale trials

    Tuesday, 21 February, 2017

    Drugmakers are hoping that much less invasive checks might be developed that use organic clues or “biomarkers” to diagnose the disease with out the necessity for a biopsy.

    “We really believe that there will be big breakthroughs that will make it much easier for physicians to diagnose the disease and subsequently to utilise the drugs in development,” says Dr Nicholson.

    One possibility is a straightforward breath check, in line with Dr Ilan Yaron, chief medical officer of Tiz Pharma, a London-based biotech group that’s about to start out testing its Nash drug in people. “The FDA does not recognise these tests yet, but it will in time,” he says.

    However, even when drugmakers discover a dependable, non-invasive approach of diagnosing the disease, there isn’t a assure that Nash victims will rush to start out taking their medicines.

    The disease progresses slowly and plenty of victims will die of one thing else; given the shortage of signs, may very well be cautious of taking a drug for all times once they really feel completely nicely.

    “I’m sceptical as to whether this is actually needed for most people,” says Ronny Gal, analyst at Bernstein. “You’re essentially trying to put into chronic treatment forever a broad population that will probably never develop the most serious form of the disease.”

    Cash-strapped healthcare techniques may resist paying for the drug in all however the sickest sufferers, predicts Mr Gal/. These quantity roughly 1.5m within the US.

    For that motive, he believes the marketplace for Nash medication might be a lot smaller than many others on Wall Street expect, and is pencilling in peak gross sales of $8bn for what he describes as a “midsize condition”.

    “If you take all the people with advanced Nash and ask how many people will end up becoming seriously ill in their lifetimes, the number could actually be very small,” he says.
259 Posts
Pagina: «« 1 2 3 4 5 6 ... 13 »» | Laatste |Omhoog ↑

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