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Home  /   Forum   /   BioPharma   /   OPXA - Merck partner

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OPXA - Merck partner

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153 Posts
Pagina: «« 1 2 3 4 5 6 ... 8 »» | Laatste | Omlaag ↓
  6. [verwijderd] 25 september 2013 21:29
    Opexa Announces Conversion of all Convertible Secured Promissory Notes into Common Stock

    September 25, 2013 6:01 AM EDT

    Overall Analyst Rating:
    BUY (= Flat)

    THE WOODLANDS, Texas--(BUSINESS WIRE)-- Opexa Therapeutics, Inc. (NASDAQ: OPXA), a biotechnology company developing Tcelna®, a patient-specific T-cell immunotherapy for the treatment of multiple sclerosis (MS), today announced the conversion of the Company’s outstanding 12% convertible secured promissory notes into shares of common stock. Notes in the aggregate principal amount of $3.185 million plus accrued interest were converted into an aggregate of 1,714,697 shares of Opexa common stock on September 24, 2013 at a conversion price of $1.91, which represented the most recent closing market price of Opexa’s common stock at the time of conversion. Opexa intends to file a Form S-3 registration statement with the Securities and Exchange Commission to register the common stock.

    The conversion of the notes also triggered the release of $500,000 of restricted cash to Opexa that has been held in a controlled account, as well as the release of the security interest in all other assets of Opexa.

    “Through the conversion of these notes, the Company is now debt-free and has strengthened its balance sheet considerably,” commented Neil K. Warma, President and Chief Executive Officer of Opexa. “Importantly, this transaction enables us to preserve cash for the continued funding of our ongoing Abili-T clinical trial in patients with Secondary Progressive Multiple Sclerosis.”

    About Opexa

    Opexa’s mission is to lead the field of Precision Immunotherapy™ by aligning the interests of patients, employees and shareholders. The Company’s leading therapy candidate, Tcelna®, is a personalized T-cell immunotherapy currently in a Phase IIb clinical development program (the “Abili-T” trial) for the treatment of Secondary Progressive Multiple Sclerosis. Tcelna is derived from T-cells isolated from the patient’s peripheral blood, expanded ex vivo, and reintroduced into the patients via subcutaneous injections. This process triggers a potent immune response against specific subsets of autoreactive T-cells known to attack myelin.
  12. [verwijderd] 9 oktober 2013 20:45
    10/08/2013 | 05:16pm US/
    Faruqi & Faruqi, LLP, a leading national securities firm headquartered in New York City, is investigating the Board of Directors of Opexa Therapeutics, Inc.

    Juan E. Monteverde, a partner at Faruqi & Faruqi, LLP, a leading national securities firm headquartered in New York City, is investigating the Board of Directors of Opexa Therapeutics, Inc. ("Opexa" or the "Company") (NasdaqCM: OPXA) for potential breaches of fiduciary duties in connection with their conduct in seeking shareholders' approval for the Company's Amended and Restated 2010 Stock Incentive Plan.

    Specifically, in the Proxy Statement filed by the Company with the Securities and Exchange Commission on October 3, 2013, the Board of Directors recommends that Opexa's shareholders vote to approve an amendment to the Company's Amended and Restated 2010 Stock Incentive Plan to increase the number of shares available for issuance thereunder by 3,000,000 shares. The issuance of the additional shares could have a substantial dilutive effect on the shares of Opexa common stock.

    Request more information now by clicking here: www.faruqilaw.com/OPXA. There is no cost or obligation to you.
  14. [verwijderd] 10 oktober 2013 18:38
    quote:

    tophound schreef op 9 oktober 2013 20:55:

    Dit is weer zo'n probeersel van een op geld belust advocatenkantoor.
    Schrikreactie: meer dan 10% omlaag.
    Bijgekocht op € 1,78.

    Dat moest $ 1,78 zijn uiteraard.
    Had een veel sterkere rebound verwacht vandaag, i.i.g. méér dan de 10% die het gisteren omlaag ging.
    Wacht het nog even af, en verkoop dan de helft.
  19. [verwijderd] 25 oktober 2013 16:40
    Opexa Therapeutics Immune Monitoring Program Recognized in Neurology Reviews
    October 25, 2013

    Opexa Therapeutics, Inc., a biotechnology company developing Tcelna, a novel T-cell immunotherapy for the treatment of multiple sclerosis (MS), announced that the Company has been featured in Neurology Reviews.

    According to a release, the article, titled "Regulation May Be Impaired in Patients With Secondary Progressive MS," was written by Erik Greb, the publication's senior associate editor, and presents data from Opexa's Immune Monitoring program that is part of its ongoing Phase IIb Abili-T trial in Secondary Progressive MS (SPMS).

    The article presents baseline data on Opexa's Immune Monitoring Program that was previously presented at the 2013 Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS) meeting. The immune monitoring data will be used to assess the impact of Tcelna in SPMS patients compared to patients receiving placebo. Opexa's data supports the finding that immune regulation appears to be impaired in individuals with SPMS. Opexa characterized the status of patients with SPMS entering the Phase IIb trial at baseline and compared the data sets to those of healthy donors. The results showed a marked difference between key biomarkers of inflammation, specifically TR1 and Treg cells, in patients suffering from SPMS versus healthy donors. The results corroborated findings in the literature and provide support for the assays being utilized by Opexa for the immune monitoring program.

    "As part of our Phase IIb Abili-T trial, we are undertaking a comprehensive immune monitoring program for all patients enrolled in the study," commented Donald Healey, PhD, Chief Scientific Officer at Opexa. "The goals of this program are to further understand the biology behind the mechanism of action for Tcelna and to possibly identify novel biomarkers that are dominant in the pathophysiology of SPMS patients. The program encompasses an analysis of various pro- inflammatory and anti-inflammatory biomarkers. We believe that the blinded data, which will be analyzed during the course of the trial, may potentially signal responders and non-responders when correlated with clinical data on completion of the Abili-T study."

    The article can be accessed here or from the home and investor relations pages of Opexa's website.

    Neurology Reviews covers news in neurology and neuroscience every month, with a focus on clinical research and practical approaches to treating Parkinson's disease, epilepsy, headache, stroke, multiple sclerosis, Alzheimer's disease, and other neurologic disorders.
153 Posts
Pagina: «« 1 2 3 4 5 6 ... 8 »» | Laatste |Omhoog ↑

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