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Home  /   Forum   /   uniQure   /   Wat is de waarde van uniQure?

uniQure« Terug naar discussie overzicht

Wat is de waarde van uniQure?

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7.824 Posts
Pagina: «« 1 ... 361 362 363 364 365 ... 392 »» | Laatste | Omlaag ↓
  2. T. Montana 25 juni 2020 09:20
    quote:

    flosz schreef op 25 juni 2020 00:59:

    [...]

    Fabry + nog wat in de maak (?)
    Waarom niet. Opvallend hoe QURE altijd verrast. BMS deal viel uit de lucht, Padua manoeuvre ook en nu dit. Volgende move waarschijnlijk even onverwacht. Saai zijn ze in ieder geval niet, gaan helemaal hun eigen weg.
  6. [verwijderd] 25 juni 2020 10:33
    Under the terms of the agreement, Spark will receive an upfront payment of $20 million and will be eligible for additional development and commercialization milestone payments of up to $260 million for multiple hemophilia B product candidates that may be developed under the collaboration. Spark will be responsible for conducting all Phase 1/2 studies while Pfizer will assume responsibility for pivotal studies, any regulatory approvals and potential global commercialization of the product. Spark is entitled to receive double-digit royalties based on global product sales.
  9. T. Montana 25 juni 2020 11:10
    SunTrust Robinson Humphrey

    BUY QURE: CSL deal takes Company in a great direction and pushes out M&A until CNS update

    What's Incremental To Our View
    We believe the CSL license agreement for EtranaDez in hemophilia B takes the Company in a great direction and pushes out M&A until we get color from
    Huntington's. We recommend buying QURE on the weakness. We’ve updated our model to incorporate terms of the license agreement: (i) hemophilia B is now recognized as royalties, and we give credit to (ii) $450M upfront cash and (iii) to additional $850M in milestone payments—$300M based on regulatory and first commercial and $550M on additional sales—from potential $1.6B. We believe open-label design of pivotal HOPE-B trial in hemophilia B would allow CSL to see data and help with license agreement as well as quell some investor concerns over immunogenicity risk with not
    excluding patients with pre-existing neutralizing Abs.

    • Bodes well for success of topline data expected in YE20
    • All 54 patients have achieved 12 weeks of follow-up
    • First patient has gone beyond 52 weeks
    • Topline 26-week data by YE20
    • Given this and recent commentary from BioMarin (BMRN, BUY), we are increasing our pricing assumption of EtranaDez from $1.5M to $2M.

    We believe the decision to license is a smart strategy for QURE.
    • Deprioritizing hemophilia A is a good decision given the competitiveness in the market
    • We believe CSL could maximize value of EtranaDez in hemophilia B given CSL’s footprint in the space
    • Helps validate QURE’s platform and manufacturing and makes M&A more likely

    We believe the license agreement with CSL Behring (CSL-AU, NR) pushes out M&A until we get color from Huntington’s disease. CEO noted that the agreement helps validate the platform and manufacturing capability and could make QURE more attractive for acquisition, but we believe PoC in Huntington's disease from the clinic will increase strategic interest. Additionally noted for a strong M&A target would be having a strong lead program, which in our view is also supported by the license agreement with CSL for > $2B ($450M upfront and $1.6B in milestones).
  12. T. Montana 25 juni 2020 13:11
    Van twitter:
    $QURE just in @ #CreditSuisse: DEAL STRONGLY POSITIVE, PT 76 Outperform, eliminates the need for Co. to build a potentially expensive global hematology commercial infrastructure for a single hemophilia product. The deal also provides substantial upfront capital to focus on the lead candidate in Huntington’s disease (AMT-130) and additional gene therapy candidates in the CNS and liver-directed space. Expecting stable bottom floor @ $61-65 as regular trading resumes, giving it 2-3 business days.Finally, we believe the deal signals high confidence in the ongoing AMT-130 Ph1/2 trial in HD. $SNY $IBB $XBI

    2 positieve analisten, CreditSuisse en SunTrust, de rest kan er vooralsnog geen sjokola van maken met koersdoelen tussen de 58-62. Hebben al hun klanten verkocht op het overname verhaal en moeten nu iets nieuws verzinnen, altijd lastig.
  16. Izette 25 juni 2020 13:40
    quote:

    pim f schreef op 25 juni 2020 13:26:

    Inmiddels voorbeurs $52,48, daarom twijfel ik een beetje mijn plan om alle stukken die ik bezit er bij opening uit te gooien. Wat doen jullie?

    Je moet het natuurlijk helemaal zelf weten, maar de kans bestaat dat je na verkoop tegen de openingskoers 51-53 de realiteit terugkeert tijdens de komende handelsuren en de koers weer ziet oplopen richting de 58-60.
    Maar dat blijft natuurlijk koffiedik kijken...
7.824 Posts
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