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GTCB - GTC Biotherapeutics - Deel 10

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  1. sappas 26 november 2007 18:07
    quote:

    SkySpam1 schreef:

    [quote=Beurs-kneus]

    www.marketwatch.com:80/news/story/sto...
    ATryn(R) - A Safe Drug Without Use of Donor Blood

    Last Update: 8:57 AM ET Nov 26, 2007Print E-mail Subscribe to RSS Disable Live Quotes
    [/quote]
    Zag hem zonet ook in m'n mailbox zitten,
    gaan ze het daar dan toch nogeens leren!!?

    "ATryn® is a new, exciting drug
    with interesting perspectives if it can be used
    for the treatment of other indications".

    $0.99
    110 K
    Sky alles wat goed is komt langzaam, soms erg langzaam maar het komt :-)

    Groetjes,

    Sappas
  2. [verwijderd] 26 november 2007 19:40
    quote:
    Mooi, mooi, zover zijn we intussen al,
    voorlopig in dit artikel nog niks over de kostprijs en het aantal patiënten.
    Alsmede nog geen verdere info betreffende de
    andere Europese landen?

    STILTE kan soms oorverdovend zijn!
  3. [verwijderd] 26 november 2007 20:00
    kostprijs ?

    U vraagt wij draaien !

    health.apmnews.com/story.php?numero=9220
    by Ailis Kane

    LONDON, Nov 21 (APM) – Leo Pharma has launched its recombinant antithrombin product ATryn in the UK for the prophylaxis of venous thromboembolism in surgery of patients with congenital antithrombin deficiency.

    The launch on Monday marks the first European launch of the first drug to be produced by a transgenic animal – in this case a goat. ATryn was developed by Leo's partner GTC Biotherapeutics and gained European approval under exceptional circumstances in August 2006.

    "It is the first ever medicine from transgenic biotechnology," said Jim Frater, Leo's marketing manager for clinical care. "It's on the borderline of amazing."

    Frater told APM that a launch in Ireland would follow shortly and the firm would roll out the product across Europe depending on commercial and product supply considerations. He said it should be available in selected European markets by the end of 2008.

    In the UK, ATryn's NHS list price will be 17,850 pounds (25,000 euros) for a pack of 10 vials. Frater said that the first two days of treatment would cost on average 2,000 pounds (2,800 euros) per day, but the overall cost of the treatment course of three days or more would vary depending on each patient.

    Once diagnosed, patients with the rare condition of congenital antithrombin deficiency must take a maintenance dose of warfarin to prevent the formation of blood clots. However, if they need to undergo surgery the warfarin must be stopped. Patients are instead given heparin activated by antithrombin during and after the surgery.

    In some European markets, a human blood product-derived version of antithrombin is available.

    Frater said that ATryn has advantages over the blood-derived version, including reducing the risk of infection by blood-borne diseases. While there is no evidence that anyone having taken human antithrombin has developed the prion disease Creutzfeldt-Jakob disease, there is theoretically a risk.

    In addition, patients on ATryn have their antithrombin levels maintained at 100% because the administration of the drug includes both bolus and continuous infusion of the product.

    FUTURE INDICATIONS

    Frater also indicated that Leo and GTC are working on potential additional indications for ATryn.

    The product is in a Phase III trial in pregnant women with congenital antithrombin deficiency who have a particularly high risk of developing thromboses. Frater said that bleeding complications and embolisms are leading causes of maternal death.

    The Phase III trial is due to be completed by the end of the year and the firm hopes to submit a regulatory filing to extend the indication by the end of next year or the beginning of 2009.

    ATryn is also in a Phase II trial for disseminated intravascular coagulation in association with severe sepsis, which is the widespread formation of clots within blood vessels.

    Leo licensed rights to ATryn for Europe, the Middle East and Canada in 2005 and GTC retains the rights elsewhere.

    GTC announced in September that the FDA had designated ATryn a "fast track product" entitled to accelerated FDA review for the hereditary antithrombin deficiency indication.

    One in 5,000 people has congenital antithrombin deficiency.

    ak/rw

    ailis.kane@apmnews.com
    [9220] 21/11/2007 13:46 GMT - INDUSTRY
  4. [verwijderd] 27 november 2007 19:54
    quote:

    ohmygod schreef:

    Tuurlijk, alles in de plus vandaag, behalve mijn biotechjes. Zo rood als een overrijpte tomaat.
    inderdaad wat een kutfonds, wat een gepruts, die hele bio-wereld is 1 grote schijtzooi.

    een serieuze belegger heeft helemaal niets te zoeken in deze branche.

    onzinnige beloftes die alleen maar kosten en niets opbrengen.

    moet je nou kijken, de dow bijna 10% in de plus en die boerderij van ons op 98 ct, zijnde 65 eurocenten.

    wij zijn veel meer waard dan pharming oreerde een jaar terug een nog over-enthousiaste tom niewberry, its a bargain at these prices.........

    de koers deed toen nog 1.17.

    stomme amerikcaan.

    mvg, domme Nederlander.
2.041 Posts
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