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Aandeel Galapagos AEX:GLPG.NL, BE0003818359

Laatste koers (eur) Verschil Volume
25,380   +1,420   (+5,93%) Dagrange 24,000 - 25,380 146.795   Gem. (3M) 111,9K

GALAPAGOS SEPTEMBER 2018

6.351 Posts
Pagina: «« 1 ... 305 306 307 308 309 ... 318 »» | Laatste | Omlaag ↓
  1. BLOO7 27 september 2018 16:40
    quote:

    Sparrow2 schreef op 27 september 2018 14:46:

    Van Money Morning

    A New "Super Drug" Will Send This Biotech Stock Skyrocketing
    By MONEY MORNING STAFF REPORTS, Money Morning • September 26, 2018

    One of the biggest waves in healthcare now is the care and treatment of the aging population. Among the more common maladies we face as we get older is arthritis – and specifically rheumatoid arthritis (RA).

    It's big deal, too. RA is the third most common type of arthritis behind osteoarthritis and gout. And it affects over 1.3 million Americans and up to 1% of the world's population, regardless of ethnic background, according to the Rheumatoid Arthritis Support Network (RASN). Women, however, are up to three times more likely than men to suffer from it.

    Fortunately, a small biotech company revealed last week that, along with its partner, its new drug to help combat rheumatoid arthritis reached its test goals in its phase 3 study. The stage is now set for a "new drug application" for U.S. Food and Drug Administration approval.

    This drug has the potential to bring incredible gains for today's biotech stock…

    The drug, called Filgotinib, has the ability to block an enzyme pathway within cells that interferes with normal processes (like cell division) that trigger an immunity response. However, the body's antibodies mistakenly attack the normal fluid in joints, causing chronic inflammation.

    Even better, the technology behind the drug shows additional promise with other inflammatory diseases, such as Crohn's disease, idiopathic pulmonary fibrosis, and atopic dermatitis.

    Credit Suisse believes Filgotinib can become a $2.5 billion drug – and that there's an 80% probability it will be approved.

    Money Morning Executive Editor Bill Patalon also thinks the potential for this biotech stock is huge. In fact, his subscribers already banked over 1,200% since he first recommended the stock in August 2011.

    And he thinks there is a lot more to come.

    This Biotech Stock Is About to Break Out Again
    Patalon is eager to re-recommend shares of Galapagos NV (NASDAQ: GLPG), the U.S.-traded shares of the Belgium-based drug maker.

    While Galapagos is a medium-cap stock with a market value of around $6 billion, it partnered with the giant Gilead Sciences Inc. (NASDAQ: GILD) to develop the Filgotinib and bring it to market. That gives it the muscle to get it done.

    Leerink Partners, an investment bank specializing in healthcare, said, "This one could be a game changer."


    Some investors might think that a stock that moved higher by that much is too richly valued. Unfortunately, that kind of thinking can keep some people from sticking with a proven winner.

    You see, in the stock market, stocks that perform well tend to continue to perform well, at least until there is reason for them to stop. With a successful phase 3 trial under its belt, this stock has nothing but good news ahead.
    Thanks Sparrow2.
    Als Leerink zo uit de hoek komt dan moet het wel een echte winner zijn.

    Hup Gala Hup.
  2. [verwijderd] 27 september 2018 17:16
    quote:

    aston.martin schreef op 27 september 2018 10:48:

    [...]

    In uw opmerking refereer eerst je zelf naar de ACR20-score.

    Nu kom met een ander verhaal dat ACR20 niet als referentie mag gebruikt worden!

    Weet je eigenlijk zelf wel wat je bedoelt en/of opschrijft?

    Ken je trouwens producten waar meer dan de helft van de patiënten wél baat bij heeft?
    Noem ze dan.

    Heb je het veiligheidsprofiel van filgotinib al eens vergeleken met dat van Xeljanz, baricitinib of upadacitinib?
    In uw ogen is misschien geen verschil?

    Ik ga het hier bij laten.
    Veel succes verder.

    Als je mijn eerste post leest schreef ik "geen of weinig baat (ACR20)". Blijkbaar is het dan niet duidelijk dat ik ACR20 onder de categorie weinig baat schuif ? Ik vind vanaf 50% verbetering pas echt overtuigend.

    Wat betreft het veiligheidsprofiel is een terecht punt. Echter wat ik jammer vind is dat ik op clinicaltrials.gov maar één kleine studie kan vinden voor filgotinib met status "completed, has results".

    Bij de resultaten worden altijd "adverse events" gepubliceerd. Voor Tofacitinib zijn die resultaten in ruime mate beschikbaar. Enig idee waarom voor Darwin1, Darwin2 en Finch2 (nog) geen resultaten op clinicaltrials.cov. staan?
  3. [verwijderd] 27 september 2018 17:24
    Analytische Denker: Dat 67% (uit m'n hoofd) ACR20 scoren, en +-50% ACR50, betekent dat die 67% dus tussen de 20 en 49% verbetering laat zien.

    En of ACR20 goed is of niet is denk ik aan de patienten. Als je heel veel last hebt van reuma, en je krijgt 30% verbetering, wellicht is dat het verschil tussen de hele dag op bed liggen en rond kunnen lopen.

    Waar het om gaat is dat de huidige reuma markt miljarden omzet genereert waarbij geen enkel medicijn betere ACR20 / ACR50 / ACR70 scores laat zien met zo'n goed veiligheidsprofiel als filgotinib, en daarom is het beste in class.

    Een puur theoretische, subjectieve opvatting at ACR20 wel of niet veel voorstelt is in feite totaal irrelevant.
  4. BLOO7 27 september 2018 17:25
    quote:

    Sparrow2 schreef op 27 september 2018 14:46:

    Van Money Morning

    A New "Super Drug" Will Send This Biotech Stock Skyrocketing
    By MONEY MORNING STAFF REPORTS, Money Morning • September 26, 2018

    One of the biggest waves in healthcare now is the care and treatment of the aging population. Among the more common maladies we face as we get older is arthritis – and specifically rheumatoid arthritis (RA).

    It's big deal, too. RA is the third most common type of arthritis behind osteoarthritis and gout. And it affects over 1.3 million Americans and up to 1% of the world's population, regardless of ethnic background, according to the Rheumatoid Arthritis Support Network (RASN). Women, however, are up to three times more likely than men to suffer from it.

    Fortunately, a small biotech company revealed last week that, along with its partner, its new drug to help combat rheumatoid arthritis reached its test goals in its phase 3 study. The stage is now set for a "new drug application" for U.S. Food and Drug Administration approval.

    This drug has the potential to bring incredible gains for today's biotech stock…

    The drug, called Filgotinib, has the ability to block an enzyme pathway within cells that interferes with normal processes (like cell division) that trigger an immunity response. However, the body's antibodies mistakenly attack the normal fluid in joints, causing chronic inflammation.

    Even better, the technology behind the drug shows additional promise with other inflammatory diseases, such as Crohn's disease, idiopathic pulmonary fibrosis, and atopic dermatitis.

    Credit Suisse believes Filgotinib can become a $2.5 billion drug – and that there's an 80% probability it will be approved.

    Money Morning Executive Editor Bill Patalon also thinks the potential for this biotech stock is huge. In fact, his subscribers already banked over 1,200% since he first recommended the stock in August 2011.

    And he thinks there is a lot more to come.

    This Biotech Stock Is About to Break Out Again
    Patalon is eager to re-recommend shares of Galapagos NV (NASDAQ: GLPG), the U.S.-traded shares of the Belgium-based drug maker.

    While Galapagos is a medium-cap stock with a market value of around $6 billion, it partnered with the giant Gilead Sciences Inc. (NASDAQ: GILD) to develop the Filgotinib and bring it to market. That gives it the muscle to get it done.

    Leerink Partners, an investment bank specializing in healthcare, said, "This one could be a game changer."

    Some investors might think that a stock that moved higher by that much is too richly valued. Unfortunately, that kind of thinking can keep some people from sticking with a proven winner.

    You see, in the stock market, stocks that perform well tend to continue to perform well, at least until there is reason for them to stop. With a successful phase 3 trial under its belt, this stock has nothing but good news ahead.
    De komende dagen een stevige stijging in het verschiet.
    Ik ben er klaar voor.
  5. [verwijderd] 27 september 2018 17:31
    Even een vraagje als leek. Ik vroeg mij of iemand kort kan uitleggen wat het primaire verschil is tussen de aex notering en nasdaq notering. Momenteel heb ik een deel van de nasdaq notering in de porto maar ik vroeg me af waarom jullie bijvoorbeeld voor het een of het ander kiezen.

    Oh en uiteraard: hup gala hup ;)
6.351 Posts
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