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Draadje vogelgriep

1.093 Posts
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  1. [verwijderd] 31 december 2005 16:57
    Glaxo seeks rule change to fight pandemic flu: FT

    Sat Dec 31, 2005 2:06 PM GMT

    LONDON (Reuters) - GlaxoSmithKline Plc is seeking dispensation from international regulators to help in the fight against a future flu pandemic, its chief executive said in an interview published on Saturday.

    Jean-Pierre Garnier told the Financial Times that authorities including the U.S. Federal Trade Commission needed to waive their usual rules to allow vaccine producers to work together.

    "We'd like to cooperate with other manufacturers to make vaccines but the U.S. needs to clear that with the FTC and the Food and Drug Administration," he said.

    Cooperation would breach current antitrust rules but could allow flu vaccine manufacturers to collaborate in order to maximize production of the best vaccine that any of them was able to produce, he said.

    Glaxo is currently racing against other vaccine makers, such as Sanofi-Aventis SA and Chiron Corp, to produce a vaccine able to fight any pandemic strain of flu that might arise from bird flu.

    Experts fear the H5N1 strain of bird flu will mutate just enough to allow it to pass easily from person to person. If it does so, it could cause a catastrophic pandemic, killing tens of millions of people, because humans lack immunity to it.

    Garnier also told the paper that all employees at Glaxo and their families would have access to Relenza, the company's inhaled antiviral drug that can help reduce the severity of flu.

    today.reuters.co.uk/news/newsArticle....
  2. [verwijderd] 31 december 2005 17:01
    Source of China bird flu death unknown

    SANMING CITY, China, Dec. 31 (UPI) -- China confirms a seventh person dead from the H5N1 bird-flu virus but can't determine where the 41-year-old woman contracted the illness.

    There had been no outbreak in Sanming City, where she worked and lived, and all poultry raised in the area had been immunized, China Daily reports.

    No virus was found in the 230 poultry culled after her death.

    Her family said she hasn't eaten poultry, been around anyone sick and she didn't have any visitors.

    The woman, known only as Zhou, caught a fever Dec. 6 and died Dec. 21.

    An unidentified official with the Ministry of Health said it waited until Dec. 29 to report the death to the public because it wanted to find the source of the bird flu.

    The World Health Organization is also investigating.

    www.sciencedaily.com/upi/?feed=TopNew...
  3. [verwijderd] 2 januari 2006 09:14
    How U.S. policy choices increase avian flu threat

    Decreased emphasis on infectious diseases make nation vulnerable, say health experts

    Posted: January 2, 2006
    1:00 a.m. Eastern
    © 2006 WorldNetDaily.com

    WASHINGTON – Policy choices by U.S. officials have made the nation more vulnerable to an avian flu pandemic and other infectious diseases, say health experts.

    "Today we face a double jeopardy from both chronic and infectious diseases, but because we forgot the public health lessons of the past, we tore down the infrastructure" that could help counter the avian flu, Dr. Susan Blumenthal, a former U.S. assistant surgeon general, told Cardiovascular Device Liability Week.

    The trouble began back in the 1960s, say Blumenthal and others, when health officials in Washington all but declared total victory over communicable diseases such as smallpox, tuberculosis and polio.

    U.S. Surgeon General William Stewart told Congress in 1969 it was time to "close the books on infectious diseases."

    What followed was a drastic decrease in public health research, funding and manpower, especially at the U.S. National Institutes of Health as funds were shifted from infectious diseases to cancer, heart disease and stroke.

    "We're not even staffed at even half the level we need to manage our day-to-day outbreaks and events in this country, let alone a challenge like pandemic flu," said Dr. Rex Archer, the director of health for Kansas City, Mo., and the president of the U.S. National Association of County Health Officials.

    Health officials say it was shortsighted 40 years ago to assume the nation's troubles with infectious diseases were over. In fact, since 1973, at least 34 new infectious microbes have emerged.

    They also suggest that President's Bush's call for $7.1 billion is not enough to offset the effects of policy choices made four decades ago.

    "What we're failing to understand is that we need consistent long-term funding that maintains a flexible, adaptable (public health system) that can respond to all health threats," said Laurie Garrett, the Pulitzer Prize-winning author of "The Coming Plague." "We just haven't been able to hold a thought in our head long enough to look at this the right way."

    Some health officials suggest the avian flu might actually present an opportunity to refocus the priorities of government.

    "There's a wave here and we should ride it," said Georges Benjamin, executive director of the American Public Health Association. "It's a terrible tragedy that's potentially there, but we should use it as an opportunity to address what we believe are long-standing areas of neglect in rebuilding the public health infrastructure."

    worldnetdaily.com/news/article.asp?AR...
  4. [verwijderd] 2 januari 2006 09:22
    Health and Human Services Secretary Mike Leavitt, appearing on CNN's "Late Edition," praised the money approved by Congress as a good step that will fund one year of preparedness efforts.

    Still, he said the U.S. is not ready, saying additional money is needed to ensure there would be enough vaccine supplies for all Americans within six months of an initial outbreak. State and local governments also need to step up efforts, Leavitt said.

    "Don't count on Washington, D.C. to manage your pandemic because it will be about your schools, it will be about your parades. You need a plan," Leavitt said, adding that he will meeting with governors in the coming weeks.

    www.washingtonpost.com/wp-dyn/content...
  5. [verwijderd] 2 januari 2006 10:06

    Bird flu tests in eastern Turkey negative-agency

    Mon Jan 2, 2006 3:41 AM ET

    ISTANBUL (Reuters) - Tests on five people, including a dead child, for possible bird flu in eastern Turkey have proved negative, the state-run Anatolian news agency reported a Health Ministry official as saying on Monday.


  6. [verwijderd] 4 januari 2006 23:58
    De wens is niet altijd de vader van de gedachte..of juist wel...
    -------------------------------------------------------------

    Turkse dode door vogelgriep

    Gepubliceerd op woensdag 04 januari 2006

    De 14-jarige Turkse jongen die afgelopen weekeinde overleed was toch besmet met de dodelijke H5N1-variant van vogelgriep.
    De Turkse minister van Gezondheid Akdag heeft dat woensdag gezegd tegenover staatspersbureau Anatolia. Ook bij een tweede persoon is vogelgriep vastgesteld. Het gaat om de eerste twee besmettingen buiten Zuidoost-Azië en China.

    Aanvankelijk beschouwden de autoriteiten het sterfgeval als mogelijk een gevolg van vogelgriep, later toch niet en nu weer wel. Akdag verklaarde dat monsters uit de longen van de jongen positief hebben gereageerd op tests.

    De tweede persoon die besmet is geraakt, is zijn zus. Zij is ernstig ziek.



  7. [verwijderd] 5 januari 2006 08:17
    quote:

    janh1 schreef:

    De wens is niet altijd de vader van de gedachte..of juist wel...
    -------------------------------------------------------------

    Turkse dode door vogelgriep

    Gepubliceerd op woensdag 04 januari 2006

    De 14-jarige Turkse jongen die afgelopen weekeinde overleed was toch besmet met de dodelijke H5N1-variant van vogelgriep.
    De Turkse minister van Gezondheid Akdag heeft dat woensdag gezegd tegenover staatspersbureau Anatolia. Ook bij een tweede persoon is vogelgriep vastgesteld. Het gaat om de eerste twee besmettingen buiten Zuidoost-Azië en China.

    Aanvankelijk beschouwden de autoriteiten het sterfgeval als mogelijk een gevolg van vogelgriep, later toch niet en nu weer wel. Akdag verklaarde dat monsters uit de longen van de jongen positief hebben gereageerd op tests.

    De tweede persoon die besmet is geraakt, is zijn zus. Zij is ernstig ziek.



    Zusje vanmorgen ook overleden.
  8. [verwijderd] 5 januari 2006 10:58
    Nog 9 mensen onder observatie in Turkije:

    "The Turkish teen, Mehmet Ali Kocyigit, died in a hospital in the southeastern Van province on Sunday.

    Huseyin Avni Sahin, chief physician at the hospital in Van, said a total of 11 people, including members of Kocyigit's family, as well as people from neighboring regions, were either being treated or under observation for suspected bird flu."

    wjz.com/health/health_story_004213631...

  9. [verwijderd] 5 januari 2006 12:01
    dat lijkt dan verdacht veel op het menselijk doorgeven......

    quote:

    Gert50 schreef:

    Nog 9 mensen onder observatie in Turkije:

    "The Turkish teen, Mehmet Ali Kocyigit, died in a hospital in the southeastern Van province on Sunday.

    Huseyin Avni Sahin, chief physician at the hospital in Van, said a total of 11 people, including members of Kocyigit's family, as well as people from neighboring regions, were either being treated or under observation for suspected bird flu."

    wjz.com/health/health_story_004213631...

  10. [verwijderd] 5 januari 2006 18:18
    Turkey's Bird-Flu Deaths Bring Virus Nearer to Europe

    The deaths come less than two weeks after Turkey reported a second wave of avian flu in poultry and mark the virus's westward progression from China and Southeast Asia. Authorities are concerned Turkey hasn't done enough to prevent human infections, which increase the risk of the virus changing into a pandemic form that may kill millions.

    ``Turkey and Western Europe have had months and months of warnings about this virus being on the way,'' Peter Cordingley, a spokesman for the World Health Organization in Manila, said over the telephone today. ``We had hoped that it would be contained to poultry and wild birds. To see what appear to be signs of human cases is a big disappointment.''
    www.bloomberg.com/apps/news?pid=10000...
  11. [verwijderd] 6 januari 2006 09:19
    Third child dies in east Turkey of bird flu
    06 Jan 2006 08:13:36 GMT

    Source: Reuters

    By Mustafa Yukselbaba

    DOGUBAYAZIT, Turkey, Jan 6 (Reuters) - A third Turkish child from the same family died of bird flu on Friday as the virus which has killed 74 people in east Asia reached the threshhold of Europe.

    Hulya Kocyigit, 11, was the sister of Mehmet Ali, a 14-year-old boy who died last weekend, and of Fatma, 15, a girl who died on Thursday.

    The children lived in a remote rural district of eastern Turkey near the Armenian border. Their six-year-old brother is also being treated for the same disease in the hospital.

    Huseyin Avni Sahin, the head doctor at Van hospital where the children died, told CNN Turk 23 people were now being treated at his hospital for suspected bird flu.
    www.alertnet.org/thenews/newsdesk/L06...
  12. [verwijderd] 6 januari 2006 12:53
    Scientists in uphill battle to fight bird flu

    Fri Jan 6, 2006 6:29 AM ET
    By Tan Ee Lyn

    HONG KONG (Reuters) - Fighting the deadly H5N1 bird flu virus is all the more difficult because experts are still figuring out how best to use Tamiflu, believed to be one of the very few defenses, scientists said.
    Roche AG's Tamiflu, generically called oseltamivir, is an anti-viral designed to fight human influenza. But tests have suggested it may be effective in reducing the severity of H5N1 and its complications if taken in higher doses.
    Still, scientists have only just begun experimenting how best to use the drug in fighting the H5N1, which health experts fear will mutate into a form that is easily transmissible among people and unleash a pandemic, killing millions.

    "The truth of the matter is, we don't really know what is the correct dose, or how many days do you have to treat with Tamiflu and what is the dose required," said virologist Robert Webster of the St. Jude's Children's Hospital in Memphis, Tennessee.

    William Chui, a pharmacologist based in Hong Kong, agrees: "The speculation in the Vietnam cases is that the recommended dosage was not high enough. Whether it's dosage, duration of treatment, they are all trial and error (for H5N1)."

    Webster said Tamiflu could only be of use against H5N1 if it is taken within one to 1.5 days of infection -- and not within 48 hours of the patient showing symptoms as advised by many experts.
    "The issue is when was the drug started in patients after they got infected. Published work on the use of Tamiflu shows it is only effective for the first day. You must begin treatment in the first day or maximally 1.5 days after initial infection. Not symptoms, that is the difficulty," Webster said.

    today.reuters.com/News/NewsArticle.as...

  13. [verwijderd] 7 januari 2006 18:13
    Two more Turkish children confirmed with bird flu
    07 Jan 2006 16:47

    GENEVA, Jan 7 (Reuters) - The World Health Organisation (WHO) said on Saturday it had confirmed that two children hospitalised in Turkey had contracted the deadly H5N1 strain of bird flu, a spokeswoman said.

    She said the children, a 5-year-old and an 8-year-old, were from the same region where three other children died from bird flu this week. She declined to give any further details.
    www.alertnet.org/thenews/newsdesk/L07...
  14. [verwijderd] 7 januari 2006 23:08
    Headline van teletekst

    129 Teletekst za 07 jan 23:00 uur
    ***************************************
    Onrust in Turkije door vogelgriep

    ***************************************
    ANKARA In Oost-Turkije groeit de onrust
    door de vogelgriep.Veel mensen melden
    zich bij ziekenhuizen voor onderzoek,
    maar die zijn daar niet op voorbereid.
    Ook beklagen veel mensen zich bij de
    lokale autoriteiten dat dode en zieke
    dieren niet worden weggehaald.

    Tot nu toe zijn drie kinderen uit één
    familie overleden aan vogelgriep.Van
    twee is het zeker dat ze de gevaarlijke
    variant H5N1 hadden.In Oost-Turkije
    zijn al meer dan 30 mensen opgenomen
    omdat ze mogelijk besmet zijn met H5N1.

    Het virus breidt zich onder de vogels
    verder uit.Deze week zijn in de buurt
    van Ankara besmette eenden gevonden.
  15. [verwijderd] 8 januari 2006 10:33
    De overleden kinderen gebruikten kippekoppen als speelgoed.....

    Spread of Turkish bird flu no surprise, experts say

    Sat Jan 7, 2006 2:26 PM ET

    WASHINGTON (Reuters) - The latest human cases of bird flu in Turkey are not unexpected, given the intense contact between the human victims and infected birds there, infectious disease experts say.

    The World Health Organization said on Saturday it had confirmed that two children hospitalized in Turkey were infected with the H5N1 strain of avian influenza.

    That makes four confirmed human cases in Turkey, the sixth country where the bird flu strain has jumped from poultry to people. A fifth child who died also tested positive for bird flu but the WHO has not yet confirmed the result.

    "I think it is the same thing as is going on in Southeast Asia," said National Institute for Allergy and Infectious Diseases Director Dr. Tony Fauci.

    The virus infected 142 people in east Asia and killed 74 before it killed the three children from the same family in eastern Turkey this week.

    A WHO spokeswoman said the two newly diagnosed children, a 5-year-old and an 8-year-old, were from the same rural region where the other three died this week.

    WHO labs will test the virus to make sure it was transmitted directly from infected chickens to the children, and not from one child to another.

    H5N1 remains mostly a disease of birds but scientists say it is mutating and has the ability to evolve into a human influenza, which would pass rapidly from person to person and could spark a pandemic -- a global epidemic.

    In Asia most cases have occurred in one or two people together at the most, and experts were concerned by the reported numbers coming in clusters in Turkey. When it became clear the cases were among families, they relaxed.

    "From the first appearance of H5N1 influenza in migrating birds in Asia, we have recognized -- and called attention to -- the possibility that they could carry the virus to other continents," Health and Human Services Secretary Mike Leavitt said in a statement earlier this week.

    "While we are concerned about (the) report of human cases of H5N1 influenza in Eastern Turkey, there is no evidence of sustained human-to-human transmission, which is the hallmark of a potential pandemic."

    Turkish officials said that in the family where three children died, they had been playing with the severed heads of chickens slaughtered after they became ill.

    "It is inevitable when you have kids playing with (infected) chicken parts that you are going to have transmission," Fauci said in a telephone interview.

    "You will have to assume that the chickens are pooping around outside the house, if not in the house," he said. "The children will be playing around that, getting it on their feet, under their fingernails, and then they will be bringing it in the house, hugging their mother and father," he said.

    Even the infection of whole families was not surprising, Fauci said. The birds could be shedding, or excreting, large amounts of virus and all members of a family could be infected directly or indirectly.

    "Sooner or later if you get infected flocks in a country you are going to get infected people," Fauci said.

    The big risk comes when the virus evolves just enough to transmit easily from one person to another. Then the greatest danger to people will be other people -- not infected birds.

    "What you will see with human-to-human transmission of the virus -- you will see infections in people who had no exposure to something infectious like feces," Fauci said.

    Children might infect other children at school or hospital workers would be getting infected.

    "What we have not seen is health-care providers getting infected," Fauci said.

  16. [verwijderd] 8 januari 2006 11:10
    Glaxo files for EU approval of pandemic flu shot
    Friday 6 January 2006, 11:37am EST

    By Ben Hirschler, European Pharmaceuticals Correspondent

    LONDON, Jan 6 (Reuters) - GlaxoSmithKline Plc (GSK.L: Quote, Profile, Research) said on Friday it had submitted a dossier to European healthcare regulators seeking outline approval to market a vaccine against pandemic flu, which experts fear may be triggered by bird flu.

    "I can confirm that a mock-up file of a pandemic influenza vaccine was submitted in December to the European authorities," spokesman David Mawdsley said in response to inquiries.

    Glaxo is the first vaccine manufacturer to make a submission under new European rules, designed to fast-track potential pandemic flu shots.

    The European Medicines Agency (EMEA) confirmed it had so far received only one application under the so-called mock-up system that allows companies to start the approval process while they are still developing experimental vaccines.

    Europe's biggest drug maker, along with several rivals, is working to develop a vaccine against the H5N1 strain of virus that has infected many birds and killed 74 people in east Asia, as well as three children in Turkey.

    The deadly H5N1 virus remains hard for people to catch but there are worries it could mutate into a form easily transmitted among humans, leading to a pandemic that could kill millions.

    A vaccine is seen as the best hope for limiting the death toll, but experts say it will be a race against time to get sufficient quantities to those who need it.

    Glaxo said last year it expected to start clinical tests of its prototype H5N1 vaccine -- which contains an adjuvant, or additive, to boost effectiveness -- during 2006.

    SANOFI, CHIRON RIVALS

    No one knows how well an H5N1 vaccine will match a future pandemic strain but it could prime a person's immune system so they will get stronger effects from a later, better-matched vaccine. France's Sanofi-Aventis SA (SASY.PA: Quote, Profile, Research) is also working on an H5N1 vaccine and has already reported promising early-stage clinical trial results showing a good immune response in humans.

    Other companies working in the field include Chiron Corp (CHIR.O: Quote, Profile, Research), which is being acquired by Novartis AG (NOVN.VX: Quote, Profile, Research).

    The EMEA, which regulates new medical treatments in Europe, expects to receive further applications from makers of pandemic flu shots during 2006.

    Thomas Lonngren, its executive director, told Reuters in an interview in October he hoped a pandemic flu vaccine would be ready for use during the 2006/7 winter flu season, if needed.

    Under the mock-up system, the agency aims to review the safety, efficacy and quality of vaccines in advance of a pandemic being declared. Once the specific pandemic virus strain is known, a variation to the core dossier could then be approved in a couple of days.

    today.reuters.com/business/newsArticl...
  17. [verwijderd] 8 januari 2006 13:23
    Birdflu jumps to northern Turkey, found in poultry
    08 Jan 2006 11:59:42 GMT

    Source: Reuters

    ANKARA, Jan 8 (Reuters) - Bird flu virus has been detected in dead chickens in two villages on Turkey's northern, industrial Black Sea coast, officials said, just days after a deadly strain killed three children in the east of the country.

    Authorities began mass culling of birds in the agricultural east last week after discovery of the first human infections with the deadly H5N1 strain beyond eastern Asia. Sunday's announcement may raise fear of a further advance towards Europe.

    Yavuz Erkmen, governor of Zonguldak region, which has a high concentration of industry and coal mining, said two villages were in quarantine, state Anatolian news agency reported.

    "No infections to humans have been detected..nearly 1,500 poultry in two villages will be culled," said Erkmen.

    Officials said it was not clear yet if the virus detected in the dead birds was H5N1.

    Turkey is the sixth country where the deadly bird flu strain has jumped from poultry to people.
    www.alertnet.org/thenews/newsdesk/B72...
  18. barst 8 januari 2006 19:29
    kijk eens aan.
    op www.vogelgriep.nl is een advertentie te vinden (zie hieronder) waarop je wordt uitgenodigd tamiflu te kopen.
    en dat blijkt uitverkocht.

    Tamiflu is op dit moment uitverkocht. Wilt u geinformeerd worden wanneer Tamiflu weer is aan te vragen, stuurt u dan een email naar tamiflu@dokteronline.com . Er is geen garantie dat de wachtlijst ook daadwerkelijk uitgeleverd kan gaan worden.
  19. [verwijderd] 8 januari 2006 20:46
    quote:

    barst schreef:

    kijk eens aan.
    op www.vogelgriep.nl is een advertentie te vinden (zie hieronder) waarop je wordt uitgenodigd tamiflu te kopen.
    en dat blijkt uitverkocht.

    Tamiflu is op dit moment uitverkocht. Wilt u geinformeerd worden wanneer Tamiflu weer is aan te vragen, stuurt u dan een email naar tamiflu@dokteronline.com . Er is geen garantie dat de wachtlijst ook daadwerkelijk uitgeleverd kan gaan worden.
    Ik meende ergens gelezen te hebben dat 1. Tamiflu niet aantoonbaar werkt... en 2. er malafide gasten zijn die nep-zooi via internet verkopen.

    mvg ivet
  20. [verwijderd] 8 januari 2006 23:36
    Human bird flu cases reach Turkish capital

    Sun Jan 8, 2006 5:01 PM ET

    ANKARA (Reuters) - Three Turks tested positive for a deadly strain of bird flu in the capital Ankara on Sunday, a new stage in the westward sweep of the disease from its east Asian origins toward major economic centers in Turkey and Europe.

    The first case of the virus jumping from birds to humans outside China and southeast Asia occurred last week in rural eastern Turkey, where three children from the same family died after contracting the highly potent H5N1 strain.

    As doctors confirmed that two children and a 60-year-old man were being treated in Ankara for the virus, Russia raised fears of the disease impacting Turkey's economy by warning its citizens against visiting the popular holiday destination.

    Doctors said the infected children, aged 5 and 2, came from Beypazari west of Ankara and had caught the virus after contact with dead wild birds. Their parents tested negative.

    Ankara is about 400 km (250 miles) east of Istanbul, Turkey's densely populated commercial and tourism hub, and from the continent of Europe. Officials said the culling of birds had begun in the Ankara districts hit by bird flu.

    Four children have also tested positive for the H5N1 strain in the city of Van, about 800 km (500 miles) east of Ankara, bringing the total number of those known to be infected in Turkey to seven.

    The state Anatolian news agency said a 5-year-old boy was admitted to hospital with suspected bird flu in Corum in central Turkey on Sunday.

    The agriculture ministry said bird flu had been detected among poultry in 15 different locations, including Istanbul.

    The children who died in Van last week almost certainly caught the virus directly from chickens, officials say.

    today.reuters.com/News/newsArticle.as...
1.093 Posts
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